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Risk of Early Death and Recurrent Stroke and Effect of Heparin in 3169 Patients With Acute Ischemic Stroke and Atrial Fibrillation in the International Stroke Trial
Stroke 32:2333-2337, Saxena,R.,et al, 2001
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Article Abstract
Acute ischemic stroke patients with AF have a higher risk of early death, which can be explained by older age and larger infarcts but not by a higher risk of early recurrent ischemic stroke, although slightly more patients with AF died from a fatal recurrent stroke of ischemic or unknown type (1.3% versus 0.9%). In patients with AF the absolute risk or early recurrent stroke is low, and there is no net advantage to treatment with heparin. These data do not support the widespread use of int ensive heparin regimens in the acute phase of ischemic stroke associated with AF.
 
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anticoagulant,treatment in CVD
atrial fibrillation
cerebrovascular accident
cerebrovascular accident,acute management of
cerebrovascular accident,recurrent
heparin
mortality
treatment of neurologic disorder

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